Monday, 24 November 2008 12:41 Health Research Board (HRB)/Medical Research Charities Group (MRCG) Project Description: Current treatments for AAT deficiency are based on augmentation therapy with recombinant or plasma-purified AAT and focus almost

Monday, 24 November 2008 12:25 Poster presentations DA Bergin, Greene CM, Taggart CC, O’Neill SJ and McElvaney NG. Activation of the EGFR by Human Neutrophil Elastase. Royal College of Surgeons in Ireland Research

We recently undertook a research project to identify the incidence of AATD in a representative sample of the general population of Ireland. This involved screening 1000 anonymised DNA samples for the presence of

Alpha-1 antitrypsin (AAT) is an antiprotease produced chiefly by the liver. Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder characterised by low serum levels of AAT and is associated with lung and liver